6,954 research outputs found

    The turbulent pressure support in galaxy clusters revisited

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    Due to their late formation in cosmic history, clusters of galaxies are not fully in hydrostatic equilibrium and the gravitational pull of their mass at a given radius is expected not to be entirely balanced by the thermal gas pressure. Turbulence may supply additional pressure, and recent (X-ray and SZ) hydrostatic mass reconstructions claim a pressure support of ∼5−15%\sim 5-15\% of the total pressure at R200R_{\rm 200}. In this work we show that, after carefully disentangling bulk from small-scale turbulent motions in high-resolution simulations of galaxy clusters, we can constrain which fraction of the gas kinetic energy effectively provides pressure support in the cluster's gravitational potential. While the ubiquitous presence of radial inflows in the cluster can lead to significant bias in the estimate of the non-thermal pressure support, we report that only a part of this energy effectively acts as a source of pressure, providing a support of the order of ∼10%\sim 10\% of the total pressure at R200R_{\rm 200}.Comment: 5 pages, 5 pages, accepted, to appear in MNRAS Letter

    A functional analysis of change propagation

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    A thorough understanding of change propagation is fundamental to effective change management during product redesign. A new model of change propagation, as a result of the interaction of form and function is presented and used to develop an analysis method that determines how change is likely to propagate. The analysis produces a Design Structure Matrix, which clearly illustrates change propagation paths and highlights connections that could otherwise be ignored. This provides the user with an in-depth knowledge of product connectivity, which has the potential to support the design process and reduce the product's susceptibility to future change

    A holistic phylogeny of the coronin gene family reveals an ancient origin of the tandem-coronin, defines a new subfamily, and predicts protein function.

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    BACKGROUND: Coronins belong to the superfamily of the eukaryotic-specific WD40-repeat proteins and play a role in several actin-dependent processes like cytokinesis, cell motility, phagocytosis, and vesicular trafficking. Two major types of coronins are known: First, the short coronins consisting of an N-terminal coronin domain, a unique region and a short coiled-coil region, and secondly the tandem coronins comprising two coronin domains. RESULTS: 723 coronin proteins from 358 species have been identified by analyzing the whole-genome assemblies of all available sequenced eukaryotes (March 2011). The organisms analyzed represent most eukaryotic kingdoms but also cover every taxon several times to provide a better statistical sampling. The phylogenetic tree of the coronin domains based on the Bayesian method is in accordance with the most recent grouping of the major kingdoms of the eukaryotes and also with the grouping of more recently separated branches. Based on this "holistic" approach the coronins group into four classes: class-1 (Type I) and class-2 (Type II) are metazoan/choanoflagellate specific classes, class-3 contains the tandem-coronins (Type III), and the new class-4 represents the coronins fused to villin (Type IV). Short coronins from non-metazoans are equally related to class-1 and class-2 coronins and thus remain unclassified. CONCLUSIONS: The coronin class distribution suggests that the last common eukaryotic ancestor possessed a single and a tandem-coronin, and most probably a class-4 coronin of which homologs have been identified in Excavata and Opisthokonts although most of these species subsequently lost the class-4 homolog. The most ancient short coronin already contained the trimerization motif in the coiled-coil domain
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